Opposition leaders in Venezuela delivered a May 2016 petition to the National Electoral Council (CNE) calling for a recall referendum, with the populace to vote on whether to remove Maduro from office.[84] On 5 July 2016, the Venezuelan intelligence service detained five opposition activists involved with the recall referendum, with two other activists of the same party, Popular Will, also arrested.[85] After delays in verification of the signatures, protestors alleged the government was intentionally delaying the process.

Opposition candidates and their supporters struggle to find places to gather without harassment from government activists and to get fuel to travel across the country.

The bitterly fought election went into a run-off on 30 October and was won by an extremely narrow margin by Lula.

In an attempt to limit the opposition’s ability to organize a campaign to unseat him, Maduro pushed for an early presidential election, which ultimately was scheduled for May 2018. The most popular likely opposition candidates were already prohibited from running for office or were in prison, and, convinced that the contest would be rigged in Maduro’s favour, opposition leaders called for a boycott of the election. Nonetheless, Henri Falcón, onetime governor and disaffected former Chávez supporter, undertook an active campaign, as did evangelical minister Javier Bertucci.

Also in August 2016, the National Election Council ruled that the opposition had collected almost twice as many signatures as were necessary for the first petition for a referendum on Maduro’s recall to be valid. However, it did not set a date for the next step in the process, which required some four million signatures to be collected in three days.

A long-standing dispute with Guyana over a large portion of that country (everything west of the Essequibo River) that had been claimed by Venezuela since the 19th century began to intensify in May 2015. The impetus for the escalating war of words was the discovery of oil offshore of the contested region.

The United States and a raft of other countries quickly recognized Guaidó as the legitimate leader of Venezuela. Another group of countries, including Russia, condemned Guaidó’s declaration and offered statements of support for Maduro, who claimed that the opposition’s action was part of a conspiracy orchestrated by the United States.

The head of Venezuela’s intelligence apparatus had, in fact, switched sides, but, before the day was over, it became clear that the military and the security forces had once again remained loyal to Maduro. The insurrection sputtered and died out. Guaidó was left to explain its failure, and López took asylum in the Spanish embassy in Caracas and ultimately fled to exile in Spain.

To be elected as President of the Republic it is required to be Venezuelan by birth, to not have another nationality, to be older than thirty years old, to be of a secular state and not having a firm court sentence and to comply with the other requirements established in this Constitution Article 227 of the Constitution of Venezuela

Leia similarmente identicamente conjuntamente: Crise na Venezuela — o contexto envolvido na grave crise humanitária que atinge este país

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In 2016, the Organized Crime and Corruption Reporting Project (OCCRP), an international non-governmental organization that investigates crime and corruption, gave President Maduro the Person of the Year Award that "recognizes the individual who has done the most in the world to advance organized criminal activity and corruption". The OCCRP stated that they "chose Maduro for the global award on the strength of his corrupt and oppressive reign, so rife with mismanagement that citizens of his oil-rich nation are literally starving and begging for medicines" and that Maduro and his family steal millions of dollars from government coffers to fund patronage that maintains President Maduro's power in Venezuela.

On 16 September 2021, the Independent International Fact-Finding Mission on Venezuela released its second report on the country's situation, concluding that the independence of the Venezuelan justice system under Maduro has been deeply eroded, to the extent of playing an important role in aiding state repression and perpetuating state impunity for human rights violations. The document identified frequent due process violations, including the use of pre-trial detention as a routine (rather than an exceptional measure) and judges sustaining detentions or charges vlogdolisboa based on manipulated or fabricated evidence, evidence obtained through illegal means, and evidence obtained through coercion or torture; in some of the reviewed cases, the judges also failed to protect torture victims, returning them to detentions centers were torture was denounced, "despite having heard victims, sometimes bearing visible injuries consistent with torture, make the allegation in court".

The announcement reflected the government’s intention to vlogdolisboa move on from a heated debate over its decision to bar opposition leader María Corina Machado from public office.